One of the first reccomendations I give on choosing hardware, is on wide drawers. Go with a single larger handle especially in the kitchen. The kitchen is a busy area and users find themselves with something in their hand when they go to open a drawer with the free hand. If there are 2 pulls on a drawer, just using one will end up tweaking the drawer in the long run. When I begin to look for a hardware collection always look at the range of sizes in that collection. I like the rule of the larger the drawer the larger the handle... or the more weight the drawer will hold the wider the stance should be that the handle provides.
Cabinet hardware is composed a variety of materials -- most of which are metal alloys. Brass hardware typically has a lacquer or plating applied to its surface that makes it very durable in a kitchen. It is antimicrobial and helps to reduce the spread of germs. Bronze hardware is also antimicrobial, offers a substantial look and feel, and works well for cabinets made of thicker woods. Stainless steel is another option because it is so durable. Pewter and nickel are popular choices, too. Or, you can choose knobs made from glass or crystal for a vintage look.
Generally speaking, I like to see a combination of knobs and handles/pulls. Knobs or handles for the doors and handles or pulls for the drawers. If you are painting your kitchen, the extra holes can be filled, sanded, and smoothed prior to painting so you can start with a clean slate and choose any hardware for your update. I say “generally speaking” because lately I’m drawn to kitchens that have all handles like this “before” photo of a kitchen we recently updated.